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PacBio

Long-read DNA sequencing systems for genomics research

Senior Staff Network Engineer

Network Engineering & AdministrationPosted on Nov 13
Full-timeMenlo Park, CA, USA$170.4k - $255.6k

About the Job

Requirements

  • At least 10 years of network engineering experience, including at least 3 years owning architecture in a multi-site enterprise.
  • A bachelor's degree in computer science, engineering, a related field, or equivalent practical experience.
  • Advanced routing and switching expertise in BGP, OSPF, VLANs, VRFs, LAG/MLAG, spanning tree, and QoS, using Cisco, Arista, or Juniper.
  • Experience with data center spine-and-leaf architecture, EVPN-VXLAN, colocation cross-connects, and carrier/cloud interconnects.
  • Demonstrated experience troubleshooting enterprise Wi-Fi performance and managing ISP/carrier services, circuit reliability, and vendor escalations.
  • Hands-on experience with next-generation firewalls such as Palo Alto Networks or Fortinet, VPN, network segmentation, and zero-trust network access.
  • Experience with identity-integrated network access using Okta, and enterprise wireless and SD-WAN solutions.
  • Experience with AWS networking, including Direct Connect, Transit Gateway, VPC design, and hybrid routing.
  • Network monitoring and logging expertise in SNMP, telemetry, NetFlow/sFlow, and syslog, plus SIEM integration.
  • Scripting and automation using Python and Ansible, with Git-based workflows.
  • Strong troubleshooting, packet analysis, technical documentation, and cross-functional project leadership.
  • Excellent interpersonal, written, and verbal communication skills.
  • Current authorization to work in the United States without present or future sponsorship.

Responsibilities

  • Own the multi-year network roadmap for LAN, WAN/SD-WAN, wireless, data centers, colocation, and cloud connectivity.
  • Design resilient, high-throughput network paths from sequencing instruments to on-premises storage and AWS/Azure compute, addressing capacity and performance bottlenecks.
  • Architect data center and colocation networks, including spine-and-leaf designs and redundant LAG/MLAG server, storage, and uplink connectivity.
  • Define network standards for hardware, topology, addressing, BGP/OSPF routing, DNS, IPAM, and reference designs.
  • Lead hybrid-cloud networking designs, including AWS Direct Connect, Transit Gateway, VPCs, and relevant Azure connectivity.
  • Serve as the senior escalation point for complex incidents; lead root-cause analysis, post-incident reviews, observability, availability objectives, and capacity planning.
  • Plan network lifecycle refreshes, site and colocation build-outs, and laboratory/data center moves with minimal business disruption.
  • Own enterprise Wi-Fi performance and reliability across corporate, laboratory, and manufacturing facilities, including coverage, capacity, roaming, interference, authentication, monitoring, and wireless optimization.
  • Manage the technical performance of ISPs and network carriers, including circuit inventories, utilization, service levels, outage escalations, redundancy, and connectivity improvements; partner with IT leadership on renewals and cost optimization.
  • Partner with Information Security on Palo Alto Networks and other firewall policies, network segmentation, NAC/802.1X, and identity-integrated zero-trust access.
  • Segment instrument, operational technology, and manufacturing networks; support validated-system change controls, audits, and ISO/SOX evidence.
  • Integrate network and firewall logs with security monitoring and incident investigations.
  • Advance network-as-code, configuration management, source control, and automated compliance using Python, Ansible, Terraform, and vendor APIs.
  • Mentor engineers, review technical designs, assess vendors and MSPs, and communicate technical risks and investments to stakeholders.

Desired Qualifications

  • CCNP/CCIE, JNCIP/JNCIE, PCNSE, or AWS Advanced Networking certification.
  • Experience in biotechnology, life sciences, medical devices, or regulated environments such as GxP/ISO 13485.
  • HPC/genomics data networking, 25/100 GbE, jumbo frames, RDMA, and research storage.
  • OT/ICS segmentation, ZTNA/SASE platforms, and NAC tools such as Cisco ISE or Aruba ClearPass.
  • Terraform, NetBox, or similar source-of-truth tools, and network observability platforms.
  • Azure networking, international site deployments, or M&A network integrations.

About the Company

PacBio

Long-read DNA sequencing systems for genomics research

PacBio designs long-read DNA sequencing systems that help researchers read complete genomes, transcriptomes, and epigenomes. Its Revio and Vega platforms use proprietary HiFi sequencing chemistry, combining the completeness of long reads with the accuracy of short reads, supported by library prep kits, reagents, and the SMRT Link software suite. Specialized tools such as Kinnex for full-length RNA sequencing and PureTarget for targeted enrichment extend the platform into human genomics, oncology, microbial, agricultural, and biopharma research. What sets PacBio apart is its focus on accuracy and completeness over raw throughput, giving scientists confidence in genomic regions that short-read technologies often miss. The goal is to enable the promise of genomics to advance human health.

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