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Mass General Brigham

Early-stage life science venture investor

Data Processing Specialist - Thoracic Surgery

Data ManagementPosted on Nov 11
Part-timeBoston, MA, USA$17.71 - $24.28 /hr

About the Job

Requirements

  • A Bachelor's degree in Management Information Systems or a related field is required; experience cannot substitute for the degree.
  • Two to three years of data analysis experience are required.
  • Hands-on experience with AWS S3 storage classes, restore requests and timing, lifecycle rules, IAM credentials, and AWS CLI or boto3 is required.
  • Experience with cost planning for storage, retrieval, and egress fees before moving data is required.
  • Experience with bulk transfer tools such as Globus, rclone, aws s3 sync, and FTPS/Aspera pulls from sequencing vendors is required, including resumable and parallel transfers and bandwidth planning.
  • Experience verifying large transfers using MD5/SHA-256 manifests, file-count and byte reconciliation, and written sign-off before source deletion is required.
  • Experience with Slurm batch jobs and job arrays; shared filesystems such as Lustre, GPFS, and NFS; quotas; Unix groups; and permissions is required.
  • Experience organizing institutional research-computing storage into fast, bulk, and archive tiers is required.
  • Experience preparing archives from large numbers of small files and determining storage requirements is required.
  • Knowledge of CRAM and its dependency on the exact reference genome, VCF, long-read data formats including Oxford Nanopore POD5/FAST5 and PacBio HiFi BAM, single-cell and spatial outputs including 10x Genomics and Xenium bundles, and whole-slide image formats including SVS, NDPI, and TIFF is required.
  • Experience handling vendor deliverables including sample sheets, QC reports, demultiplexing, and run, lane, and library IDs is required.
  • Experience with REDCap or a biobank LIMS such as OpenSpecimen or FreezerPro, including barcoding, freezer inventory, and chain of custody, is required.
  • Experience modeling the chain from patient to specimen/block, section/aliquot, library, sequencing run, and file, including a data dictionary and controlled vocabularies, is required.
  • Ability to handle patient data in accordance with HIPAA, IRB protocols, coded (de-identified) sample IDs, access control, data use agreements, and MGB data-security policy is required.
  • Ability to use Git and maintain re-runnable, logged scripts, clear READMEs, and runbooks is required.
  • Ability to manage a multi-month migration by inventorying data, agreeing priorities, maintaining a tracking sheet, and providing regular status updates is required.
  • Ability to support wet-lab staff and work with sequencing vendors and cores is required.

Responsibilities

  • Acquire data from primary or secondary data sources and maintain databases and data systems.
  • Identify, analyze, and interpret trends or patterns in complex data sets and clean data to correct problems.
  • Perform other duties as assigned by the PI.
  • Comply with policies and standards as assigned by the Research Manager.

Desired Qualifications

  • Prior experience depositing data in SRA, dbGaP, GEO, or EGA for publications, or willingness to learn, is preferred.
  • A Master's degree in a related field is preferred.

About the Company

Mass General Brigham

Early-stage life science venture investor

Mass General Brigham Ventures funds early-stage life science ideas arising from Mass General Brigham’s research network. It provides first access to deal flow and proprietary rights, backing the formation and growth of new companies and technologies. It uses capital and support to help translate bold innovations into drugs and medical technologies that improve patient outcomes worldwide.

Company size
1-10
Company stage
Not listed
Total funding
$1.9B
Headquarters
Cambridge, MA
Founded
2008

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