Full-Time

Mechanical Engineer 2

Helogen

Helogen

11-50 employees

Autonomous orbital biology research platforms

Compensation Overview

$140k - $160k/yr

No H1B Sponsorship

Los Angeles, CA, USA

In Person

Candidates must be based in Los Angeles or willing to relocate there.

Category
Mechanical Engineering (1)
Required Skills
Robotics

Get referred to Helogen

See people who can refer or advise you

Requirements
  • Demonstrated experience in mechanical and structural analysis.
  • Strong experience in mechanical computer-aided design modeling and design.
  • Deep understanding of materials science, material properties, and compatibility, with an emphasis on polymers.
  • Familiarity with Design for Manufacturing principles, computer-aided manufacturing processes, and fabrication techniques.
  • Proficiency with rapid prototyping methods, including fused deposition modeling, stereolithography, laser cutting, and machining.
  • Comfort using mechanical analysis software tools such as ANSYS or equivalent.
  • Ability to evaluate design tradeoffs, quantify risks, and make sound engineering decisions.
  • Hands-on experience building, testing, and iterating physical systems.
Responsibilities
  • Design and analyze mechanical hardware for current and future spaceflight bioinstrumentation, including electromechanical and microfluidic systems, and evaluate design tradeoffs to support engineering decisions.
  • Develop, test, and document system prototypes.
  • Apply rapid prototyping techniques, including fused deposition modeling, stereolithography, laser cutting, and machining from desktop-level computer numerical control to full vertical machining centers.
  • Develop computer-aided design models, engineering drawings, and technical documentation to support fabrication and manufacturing.
  • Partner with manufacturing teams to complete Design for Manufacturing reviews and transition designs into production.
  • Contribute to assembly, integration, and test efforts for full flight systems.
Desired Qualifications
  • Experience designing hardware for aerospace, spaceflight, robotics, medical devices, laboratory instrumentation, or other complex engineered systems.
  • Knowledge of electromechanical systems, microfluidics, precision mechanisms, or instrumentation.
  • Experience supporting hardware through assembly, integration, and test activities.
  • Experience with robotics, automotive projects, machining, electronics, fabrication, or other technical hobbies.
  • Startup or early-stage engineering experience.

Helogen provides autonomous, space-based biology platforms with orbital laboratories for high-throughput drug discovery and biomanufacturing. Its labs use proprietary tools—Multi-Modal Culture Analyzer, Sequencer, and Bioreactor—to grow, monitor, and manufacture biological systems in microgravity via remotely operated operations. The company differentiates itself through end-to-end space assays with commercial rights to materials from partnerships, plus notable collaborations with Memorial Sloan Kagan? Memorial Sloan Kettering and NASA, and the acquisition of Vellon Space to expand MEAP coverage, enabling faster, scalable space biology. Helogen’s goal is to make space research faster, cheaper, and more accessible to accelerate early-stage drug development, tissue engineering, and aging research.

Company Size

11-50

Company Stage

Seed

Total Funding

$7.9M

Headquarters

New York City, New York

Founded

2022

Get referred to Helogen

See people who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • Helogen announced two October 2026 missions, signaling active commercial execution.
  • Helogen says eight 2026 missions support a Series A and regulatory pathway.
  • LambdaVision's May 2026 partnership extends Helogen's biomaterial pipeline into retina manufacturing.

What critics are saying

  • Helogen still lists only $7.1 million raised, forcing a Series A before 2027.
  • A single October 2026 launch failure can erase months of biology timelines.
  • FDA-grade orbital manufacturing depends on unproven repeatability, making mission failure existential.

What makes Helogen unique

  • HEL-IOS automates closed-loop biology, sequencing, and analytics in orbit without continuous crew intervention.
  • October 2026 missions target GMP-grade biomaterials and FDA-facing quality data.
  • Starlab, LambdaVision, MSK, NASA, and AgResearch anchor a differentiated validation stack.

Help us improve and share your feedback! Did you find this helpful?

Benefits

Unlimited Paid Time Off

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

401(k) Retirement Plan

Growth & Insights and Company News

Headcount

6 month growth

33%

1 year growth

33%

2 year growth

20%
FinSMEs
Sep 4th, 2026
Helogen raises $7.1M to manufacture biomaterials for medical implants in space

Helogen, a New York-based space biotechnology startup, raised $7.1 million in seed funding co-led by RRE Ventures and Oceans, with participation from One Way Ventures and Blisce. The company develops automated laboratory hardware and robotic manufacturing equipment that operates in microgravity to synthesise advanced biomaterials for medical implants. Its platform uses remote-controlled bioreactors and crystallisation chambers inside orbiting satellite modules, leveraging the weightless environment of space to achieve near-perfect molecular structures and material purity. Led by chief executive officer Shishir Bankapur, Helogen will use the capital to scale its automated in-orbit fabrication hardware, expand its aerospace engineering and molecular biology teams, and accelerate customer-funded biological research programmes. The cloud-linked system provides biopharma enterprises and academic research teams with commercial access to design next-generation medical implants.

GlobeNewswire
Apr 30th, 2025
Helogen Acquires Vellon Space in India

Helogen Corporation has acquired Vellon Space, a Bengaluru-based startup, to expand its reach into India's space and biotechnology sectors. The acquisition aims to leverage Vellon's expertise and collaborations with ISRO and other institutions to offer advanced orbital biomanufacturing and drug development technologies. India's pharmaceutical market, valued at $58 billion, is projected to reach $120–130 billion by 2030. The terms of the transaction remain confidential.