Senior Research Associate 1 – Compound Management

The Position

The Drug Discovery team is looking for a Senior Research Associate I, Compound Management to join our group. In this role, you will help power the discovery of new medicines by ensuring scientists across the organization have access to the high-quality compounds and samples needed to advance research programs. Your work will directly enable scientists to advance programs aimed at translating novel genetic insights into lifesaving medicines.

You will partner closely with colleagues across Drug Discovery, including Chemistry, Biology, and other cross-functional teams, to manage compound inventory, support sample management workflows, and help maintain the efficient operation of our compound management capabilities. As a key member of a collaborative and growing organization, you will contribute to the infrastructure and processes that drive our research and drug discovery goals.

This role offers a unique opportunity to expand your technical expertise, develop strong cross-functional relationships, and grow your career within a dynamic biotech environment. If you are detail-oriented, analytical, and motivated to make an impact, you will find meaningful opportunities to learn and contribute as the company continues to grow.

This position reports to the Director of Chemistry.

The Impact You’ll Have

• Manage the weighing, storage, maintenance, and distribution of compound inventories.
• Responsible for the operation of automated laboratory equipment to support the processing of samples.
• Proactively monitor the compound request queue and fulfill the requests in a timely manner.
• Partner with Facilities Department for the shipping and tracking of compounds both locally and internationally to our collaborating CROs.
• Routinely perform sample QC checks and analysis. 
• Coordinate with R&D operations, vendors, and CROs to procure, track, and process samples to support internal and external studies.
• Assist in the development and implementation of workflows to support error-free high throughput compound processing.
• Coordinate cross-departmentally for routine or ad hoc compound plating.
• Maintain lab consumable inventory.

What We’re Looking For

• Minimum of a BS degree in Biological or Chemical Sciences with 3+ years of experience in small molecule compound handling and processing.
• Experience with laboratory automation, specifically liquid handling platforms like Tecan EVO, Labcyte ECHO or similar.
• Experience with troubleshooting and maintenance of instrumentation platforms and automated integrated systems. 
• Experience with optimizing compound processing workflows including knowledge and use of Mosaic is desired. 
• Innate attention to detail, organization skills, ability to multi-task and work across initiatives simultaneously under tight deadlines
• Effective communication skills and strong interpersonal skills to engage in cross-functional collaboration and teamwork. 

About Maze Therapeutics

Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease.

Our People

Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. 

Our Core Values

Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission. 

Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.

Stand True – Our integrity is foundational; it guides us no matter the obstacle.

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The expected annual salary range for employees located in the San Francisco Bay Area is $105,000 - $128,000. Additionally, this position is eligible for an annual performance bonus.

Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.

Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.

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