Full-Time

Senior Director

Compound Management, Medicinal Chemistry

Confirmed live in the last 24 hours

Revolution Medicines

Revolution Medicines

201-500 employees

Develops targeted therapies for RAS cancers

Biotechnology
Healthcare

Compensation Overview

$235k - $281kAnnually

Expert

San Carlos, CA, USA

Hybrid position requiring in-office presence.

Category
Biology Lab & Research
Biology & Biotech
Requirements
  • BS/MS or equivalent degree in chemical, biological, engineering sciences or related field with 10+ years working full time in an industrial laboratory setting.
  • Familiarity with modern compound management and modern data systems preferred
  • Proven track record of both compounds and lab management and people leadership across multi-disciplinary drug discovery teams.
  • Managing, coaching and mentoring scientists across the discovery function in order to develop their skills and build RevMed’s organizational capabilities.
  • Innovative team-player with high energy for our fast-paced environment.
  • Strong understanding of chemistry and familiarity with chemistry platforms such as Chemdraw, InstantJChem and Marvin Draw.
  • Demonstrated ability to plan and achieve research goals as part of an interdisciplinary team.
  • Excellent written and verbal communication skills to work with interdepartmental teams.
  • Evidence of successful coaching, mentorship and development of both individuals and teams in order to build long-term organizational capability.
Responsibilities
  • Lead all compound management and Chemistry Lab operation functions including compound registration, inventory, storage, reagent inventory, sample tracking, distribution, communication with collaborators, and sample data management.
  • Establishing strategies that enable growth and expansion of all Compound management, Automation, and Lab management functions.
  • In close collaboration with Discovery Sciences, Biology, and Pharmacology functions enable further optimization of compound management workflows and expanding HTS screening support.
  • Work with external partners to further optimize compound archive and storage, distribution, and inventory management with a view to data safety and company growth.
  • Evaluate and optimize tools that support internal processes and improve user experience. In addition, support changes to software, hardware, and procedures. Proactively seek improvements to usability of these systems and production timelines.
  • Create and maintain SOPs for critical processes.
  • Continue customization of sample software and work closely with vendors to solve problems.
  • Maintain effective oral and written communication to research team members and provide support to ensure timelines are met.

Revolution Medicines develops treatments specifically for cancers caused by RAS gene mutations, which are common in difficult-to-treat cancers like pancreatic, colorectal, and lung cancers. Their main product line includes RASON Inhibitors, which target and inhibit RAS proteins that contribute to cancer growth. The company uses a Tri Complex Inhibitor platform to create these specialized therapies. Unlike many competitors, Revolution Medicines focuses solely on RAS-driven cancers, allowing them to concentrate their research and development efforts in this niche area. Their goal is to transform cancer treatment by providing effective targeted therapies for patients suffering from these challenging conditions.

Company Stage

IPO

Total Funding

$219.8M

Headquarters

Redwood City, California

Founded

2014

Growth & Insights
Headcount

6 month growth

12%

1 year growth

36%

2 year growth

137%
Simplify Jobs

Simplify's Take

What believers are saying

  • Acquisition of EQRx adds over $1 billion in capital for research and development.
  • Increased interest in targeted therapies boosts investment and partnership opportunities.
  • Shift towards personalized medicine aligns with their focus on genetic mutations.

What critics are saying

  • Integration challenges with EQRx could disrupt operations and delay timelines.
  • EQRx's pricing model may conflict with Revolution Medicines' market strategies.
  • $600M public stock offering may dilute existing shareholder value.

What makes Revolution Medicines unique

  • Revolution Medicines uses a unique method to synthesize pharmaceutically optimized natural compounds.
  • Their Tri Complex Inhibitor platform targets RAS proteins driving cancer growth.
  • Exclusive licensing with the University of Illinois enhances their proprietary technology.

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