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Profluent

AI-designed bespoke proteins for genetic therapies

Machine Learning Scientist - Bioml

AI ResearchConfirmed live in the last 24 hours
Full-timeEmeryville, CA, USA

About the Job

Requirements

  • A PhD or equivalent industry experience in Computer Science, Machine Learning, Natural Language Processing, Applied Math, Computational Biology, Statistics, or a related field.
  • Experience conceiving, implementing, and evaluating novel machine learning techniques at the intersection with biology.
  • Publications at major machine learning conferences such as NeurIPS, ICML, or ICLR, or scientific journals such as Nature, Science, Nature Biotechnology, Nature Methods, or PNAS.
  • Experience with modern deep learning frameworks such as PyTorch or JAX.

Responsibilities

  • Design and develop predictive and generative models incorporating domain-specific evolutionary and experimental data.
  • Use large-scale protein and nucleic acid data to train specialized models for protein understanding and design.
  • Curate relevant datasets and design tasks for rigorous evaluation of generative models.
  • Collaborate with machine learning and protein design teams to adapt and apply techniques for experimental validation.
  • Implement, analyze, and interpret computational approaches and present results to colleagues in regular update meetings.
  • Collaborate across an interdisciplinary team spanning biology and machine learning to help shape the company's scientific and strategic vision.

Desired Qualifications

  • Familiarity with foundational biology of proteins and nucleic acids.
  • Experience developing machine learning models for proteins, including language models, structure prediction, or design.
  • Experience with cloud compute platforms such as GCP, AWS, Azure, or OCI.
  • Previous experience extracting and curating data from bioinformatics sources.
  • Familiarity with wet-lab experimental assays and their limitations.
  • Three to five years of industry experience.

About the Company

Profluent

AI-designed bespoke proteins for genetic therapies

Profluent.bio designs custom proteins for genetic medicines using artificial intelligence. Its core offering is bespoke protein solutions tailored to therapeutic needs for pharmaceutical and biotech partners, helping advance treatments for genetic diseases. The product works by applying AI to optimize protein design, effectively decoding the “language of life” to create proteins that extend beyond natural or existing patented options. Partners collaborate on projects, with revenue coming from upfront fees, milestones, and royalties on successful commercialization of therapies that use their proteins. The company differentiates itself by combining AI-driven protein design with a partnership model in the gene editing and synthetic biology space, aiming to deliver more effective and precise treatments while enabling cost-efficient development. The goal is to accelerate genetic medicine by providing optimized proteins that enable new or improved therapies for genetic diseases.

Company size
51-200
Company stage
Late Stage VC
Total funding
$149M
Headquarters
Emeryville, CA
Founded
2022

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