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Noetik

AI-native biotechnology company developing precision immunotherapies

Histology Manager

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeSouth San Francisco, CA, USA

About the Job

Requirements

  • A bachelor's degree in biological sciences, histotechnology, or a related field is required.
  • Extensive hands-on histology experience, including FFPE tissue preparation and sectioning, is required.
  • Demonstrated expertise sectioning a broad range of human tissue types, including challenging specimens, is required.
  • A strong understanding of common histology workflows and artifacts, including tissue microarrays, and the ability to troubleshoot complex issues are required.
  • Experience managing a histology team supporting high-throughput tissue workflows is required.
  • Experience managing laboratory workflows, priorities, and capacity, including working with laboratory information management systems, is required.
  • Strong organizational skills and attention to detail, particularly when working with high-value or limited tissue samples, are required.
  • A strong track record in exceeding expectations, with a drive for efficiency, is required.
  • The ability to work effectively in a fast-paced, highly collaborative, and dynamic environment is required.
  • Strong written and verbal communication skills are required.

Responsibilities

  • Lead day-to-day histology operations, including FFPE reembedding, sectioning, H&E staining, and related tissue processing workflows.
  • Serve as a technical resource for difficult or complex histology issues.
  • Establish and maintain standards for each step of the histology workflow, troubleshoot all aspects of the workflow, and lead root cause investigations where appropriate.
  • Ensure consistent production of high-quality tissue sections for downstream assays, including H&E, immunostaining, and spatial transcriptomics.
  • Partner with downstream assay teams to understand requirements and ensure appropriate tissue preparation.
  • Communicate capacity constraints, technical risks, and sample quality issues to stakeholders.
  • Evaluate and implement new histology equipment, consumables, technologies, workflows, and automation to enable histology operations at scale.
  • Manage, mentor, and develop the histology team.
  • Establish clear expectations for technical performance, quality, productivity, and laboratory procedures.
  • Provide regular feedback, coaching, and career development for team members.
  • Develop onboarding and training programs for new histology team members.
  • Foster a collaborative, quality-focused, and continuous-improvement culture.

About the Company

Noetik

AI-native biotechnology company developing precision immunotherapies

Noetik is an AI-native biotechnology company that develops precision cancer immunotherapies. It uses advanced machine learning to analyze complex tumor-immune interactions and builds foundational, multimodal models of cells and tissues from large-scale human data. This enables the design of immunotherapies tailored to individual patients. The company partners with pharmaceutical companies and healthcare providers, licensing technologies, conducting research collaborations, and selling proprietary therapeutic solutions. Unlike many firms that apply AI to existing processes, Noetik creates AI-driven models to guide drug discovery and therapy development, aiming to push the capabilities of precision medicine beyond what humans can achieve. The overarching goal is to advance cancer treatment by delivering AI-powered, personalized therapies and enabling clients to develop and commercialize these solutions.

Company size
51-200
Company stage
Series A
Total funding
$54M
Headquarters
South San Francisco, CA
Founded
2022

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