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Helical

AI-driven in-silico lab for drug discovery

Senior Finance Manager

Corporate Finance & FP&APosted on Nov 10
Full-timeLuxembourgNo salary listed

About the Job

Requirements

  • A total of 4–6 years of experience, including 2–3 years in audit, accounting, or corporate finance, with a strong accounting foundation.
  • Experience using a finance operations stack, such as accounting software, accounts payable or expense tools, cash management tools, or subscription tools.
  • Experience building budgets, forecasts, and financial models and turning them into clear reporting for leadership and investors.
  • Fluent English.
  • Based in Luxembourg or London, or willing to relocate.
  • Take ownership of work and be accurate and pragmatic about priorities.
  • Prefer simple, automated processes and be fluent with artificial intelligence tools.
  • Explain the reasoning behind decisions and numbers clearly to non-finance colleagues and investors.

Responsibilities

  • Own accounting and month-end close across the UK and Luxembourg entities, including intercompany flows, consolidation, and transfer pricing, in partnership with external advisors.
  • Own compliance in both countries, including statutory accounts, value-added tax, corporate tax, payroll filings, and annual audits.
  • Build and run the annual budget and a rolling forecast; track actuals against plan and flag variances early.
  • Manage cash and keep the runway forecast up to date.
  • Prepare monthly management reporting and board and investor packs.
  • Support the Series A process, including the financial model, data room, due diligence, and investor reporting after the round.
  • Run finance operations, including payables, receivables, invoicing, expenses, card spend, and approvals, automating processes where possible.
  • Build and refine scalable finance processes and controls, including expense policy, approval flows, purchasing, and finance tools.
  • Cover human resources and administrative operations, including payroll, benefits, contracts, employee records, and entity and corporate administration, in coordination with the Operations team.

Desired Qualifications

  • An accounting qualification such as ACA, ACCA, CPA, or expert-comptable.
  • Two to three years of experience in a start-up, scale-up, or other dynamic environment during a period of growth.
  • Experience with the finance operations stack, ideally in the small and medium-sized enterprise category.
  • Hands-on experience with a multi-entity setup, ideally across the UK and Luxembourg or the UK and an EU country.
  • Exposure to a fundraising process, including due diligence, data room, and investor reporting.
  • French or German language skills.
  • Experience in biotech, life sciences, deep tech, or artificial intelligence, or interest in the company’s work.

About the Company

Helical

AI-driven in-silico lab for drug discovery

Helical builds a virtual AI lab that turns biological foundation models into reproducible, decision-ready in-silico workflows for pharmaceutical R&D. The platform has a Virtual Lab for biologists and translational scientists and a Model Factory for ML engineers, and both share data, models, and results to bridge computational predictions with biological validation. It enables target identification, biomarker discovery, and therapeutic design by running computational workflows that generate actionable insights which are validated experimentally. The company differentiates itself by integrating biology and machine learning in a collaborative platform that creates an evidence layer linking predictions to validation, and by working with top pharma customers to shorten discovery timelines from months to days.

Company size
11-50
Company stage
Seed
Total funding
$12.4M
Headquarters
Luxembourg, Luxembourg
Founded
2023

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