S

Substrate Bio

Autonomous AI-driven wet labs for biological experimentation

Member of Technical Staff - Software

Software EngineeringConfirmed live in the last 24 hours
Full-timeLondon, UKNo salary listed

About the Job

Requirements

  • Have shipped production systems that other people depend on.
  • Work across the stack, including backend services and APIs, data pipelines, and front-end development to ship usable interfaces.
  • Be fluent in at least one programming language used to build production services.
  • Build with coding agents by default and evaluate their output critically.
  • Use rigorous continuous integration and continuous delivery and automated testing.
  • Own architecture, reliability, observability, and on-call responsibilities end to end.

Responsibilities

  • Build the core software behind the lab, working across the stack with the founding software engineer and wider team.
  • Develop data infrastructure and the data model for ingesting, processing, and outputting data.
  • Build APIs and services for other systems and agents to use.
  • Develop workflow orchestration and systems that track lab activity in real time.
  • Build data pipelines with audit logging to ensure activity is accounted for.
  • Develop the platform, including data-serving abstractions, authentication and access control, and observability.
  • Write production code, help set architecture and engineering culture, and work closely with scientists and the team learning from generated data.
  • Get productive in the codebase and ship an initial change following the team's review and deployment practices.
  • Take ownership of a service or surface within the team.
  • Ship a meaningful part of the owned service or surface into use by scientists and connect the work to the shared data model so data is captured and traceable.
  • Own the service or surface end to end, including reliability, observability, and on-call.
  • Help shape architecture and the team's next hires as it scales.

Desired Qualifications

  • Experience working at the software-to-physical-world boundary, such as lab automation, robotics, manufacturing, logistics, scientific instruments, or energy.
  • Experience with orchestration, scheduling, or workflow-engine work and distributed systems at scale.
  • Experience with data-intensive systems, including pipelines, ontologies or knowledge graphs, and provenance or lineage.
  • Early-stage or founding-engineer experience at a venture-backed company.

About the Company

Substrate Bio

Autonomous AI-driven wet labs for biological experimentation

Substrate Bio operates AI-native data-production infrastructure for biology, connecting computational models with real-world experimentation. The company runs a network of autonomous, robotics-powered wet labs, starting in London with a second planned for San Francisco, running standardized experiments with full provenance, metadata, and quality control. Researchers access the labs via API, submitting experiment parameters and receiving structured data and metadata, while foundation models help design assay selections, cell systems, and gene panels. What sets Substrate Bio apart is its closed feedback loop, where better data improves its models and better models design better experiments. The goal is to make biological experimentation as programmable and scalable as computation itself.

Company size
Not listed
Company stage
Not listed
Total funding
Not listed
Headquarters
Not listed
Founded
Not listed

Recently Posted Jobs

Explore more opportunities at Substrate Bio

See more jobs