Celldex develops antibody-based therapies for inflammatory, allergic, and autoimmune diseases, focusing on mast cell biology. Its lead program barzolvolimab is a humanized monoclonal antibody that blocks KIT signaling to reduce mast cell activity and inflammation, with additional antibodies in development that engage the immune system or modulate disease pathways. It differentiates itself by concentrating on KIT/mast cell biology within antibody therapies and pursuing a mix of partnerships, licensing, and own products. Its goal is to bring therapies to patients that lower inflammation and autoimmunity by targeting mast cells and related pathways.
Company Size
201-500
Company Stage
IPO
Headquarters
Hampton, New Jersey
Founded
1983
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