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Nautilus Biotechnology

Proteomics platform for drug target prioritization

Senior Accountant

Financial AccountingConfirmed live in the last 24 hours
Full-time$114k - $168k /yrIn-person

About the Job

Requirements

  • A minimum of 4+ years of progressive accounting experience, with meaningful exposure to general ledger accounting, month-end close, and accounts payable.
  • A degree in Accounting or Finance, or equivalent experience.
  • Solid working knowledge of U.S. generally accepted accounting principles, including accrual accounting and prepaid expense treatment.
  • Experience operating within a Sarbanes-Oxley-compliant environment, including ownership of controls documentation and testing.
  • Experience working with enterprise financial systems.
  • Strong analytical skills and proficiency in Excel, including VLOOKUP, SUMIFS, INDEX/MATCH, and pivot tables.
  • Ability to manage competing deadlines in a fast-paced, high-growth environment.
  • Excellent communication skills and a collaborative working style, with comfort partnering with cross-functional teams and managing remote/offshore relationships.
  • A continuous improvement mindset and flexibility to grow with the company.

Responsibilities

  • Execute the monthly accounting close process, including preparation of journal entries for accruals, prepaids, and other general ledger accounts; ensure entries are accurate, well-supported, and posted on schedule.
  • Prepare and review balance sheet account reconciliations monthly; investigate and resolve reconciling items in a timely manner.
  • Maintain a strong internal control environment in accordance with Sarbanes-Oxley 404 requirements; prepare and update process narratives, risk control matrices, and supporting documentation for assigned control areas.
  • Identify opportunities to improve close efficiency, reduce manual work, and strengthen controls; drive implementation in collaboration with the Accounting team and cross-functional stakeholders.
  • Partner with FP&A and cross-functional teams on accrual estimates, prepaid amortization schedules, and other inputs for month-end close.
  • Support the preparation of work papers and schedules for quarterly reviews and the annual audit.
  • Assist with the implementation of accounting policies, system improvements, and other projects as the company scales from pre-commercial to commercial operations.
  • Participate in or lead ad-hoc tasks and projects as needed.

Desired Qualifications

  • CPA is preferred.
  • Experience with NetSuite is a plus.

About the Company

Nautilus Biotechnology

Proteomics platform for drug target prioritization

Nautilus Biotechnology develops a proteomics platform that maps the human proteome to speed up drug discovery. The platform analyzes thousands of proteins across biological samples to reveal which drug targets are most likely to succeed in clinical trials, helping researchers prioritize targets with higher potential. The company sells the platform and related services to pharmaceutical companies, research institutions, and biotech firms, operating on a B2B model. Unlike tools that focus only on genes or small-molecule data, Nautilus provides direct protein-level insights at large scale, combining deep proteome coverage with analytics to reduce time and costs in target discovery. Its goal is to unlock the proteome to enable breakthroughs in biology and medicine and to improve global health outcomes by accelerating and improving drug development.

Company size
51-200
Company stage
IPO
Headquarters
Seattle, WA
Founded
2016

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