In Vivo Technical Specialist
Nosis Bio
In Vivo Technical Specialist
Nosis Bio
Biotech firm delivering cell-targeted RNA therapeutics
Nosis Bio is a well-funded biotech startup exclusively focused on cell-specific delivery of RNA therapeutics. We are an all-scientist team of biologists, chemists, and machine learning experts who believe targeted extrahepatic delivery is the key to making RNA therapies the standard of care for a wide range of chronic diseases. We combine deep expertise in receptor biology, generative AI, and high-throughput in vivo data generation to accelerate the development of RNA therapeutics for new tissues. We are addressing a major unmet need across the industry and actively partner with pharmaceutical companies, research institutions, and biotech companies.
We are seeking a Technical Specialist / Research Associate to conduct in-vivo experiments to evaluate the pharmacokinetic (PK), pharmacodynamic (PD), and efficacious properties of therapeutic candidates. The successful candidate will have hands-on experience with in-vivo animal studies and will work closely with multidisciplinary teams to support various drug discovery projects. This is an on-site, in person position.
Perform in-vivo PK/PD and efficacy studies in animal models, including intravenous (IV) and subcutaneous dose administration, blood sampling, tissue collection, and necropsy.
Adopt new techniques and develop disease models for in house use.
Ensure proper animal handling and dosing techniques, following established protocols and ethical guidelines.
Collect, organize, and document experimental data accurately and maintain laboratory records in compliance with company protocols and regulatory standards.
Stock/maintain consumables and reagents necessary for experiments.
Collaborate with cross-functional teams, including biology, chemistry, and translational science, to support project goals and timelines.
What we’re looking for:
Ability to work on site in our lab spaces located in the California Bay Area – Research park at Marina Village (Alameda, CA)
Motivated and proactive with strong problem-solving skills.
Team-oriented and open to collaboration across scientific disciplines.
Title and track is dependent on academic and professional experience – we recruit diverse backgrounds including those with academic, non-profit, and industry experiences!
General Requirement: AS or BS degree with 3+ years in vivo experience (industry or academia) and 1+ years experience in an industry (or similar) environment
Nosis Bio develops cell-targeted RNA medicines using its Connexa platform, which combines physics-informed deep learning, generative AI, and high-throughput biochemistry to design Targeted Delivery Vehicles for RNA therapies. Connexa builds a receptome atlas mapping human receptors, identifying over 2,900 cell-specific targets to allow gene silencing in precise cell types, including difficult tissues like the CNS. The company pursues a wholly owned pipeline while partnering with big pharma to apply its platform to high-value indications. Its goal is to enable safer, re-dosable RNA medicines that reach previously hard-to-target tissues, expanding treatment options for fibrosis, immune and cardiovascular diseases.
Explore more opportunities at Nosis Bio