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ZBiotics

ZBiotics

Genetically engineered probiotics targeting acetaldehyde

Area Sales Manager

Full-Time
$115k - $135k/yr

+ Equity

Mid
Rhode Island, USA+1 more

More locations: Massachusetts, USA

Remote

Remote within Massachusetts and Rhode Island, with 3–4 days per week in the trade.

About the job

Requirements
  • At least 3–5 years of beverage-alcohol industry experience representing a supplier or distributor within the Massachusetts craft beer, spirits, or wine markets.
  • A proven track record of managing Massachusetts and Rhode Island off-premise retail accounts, with a focus on independent off-premise retailers and grocery outlets.
  • Demonstrated success in the Massachusetts and Rhode Island on-premise sector, specifically with high-end hotels, premium restaurants, and bars.
  • Experience educating staff at on- and off-premise retail accounts, including small and large groups.
  • Understanding of retailer business needs in both on- and off-premise channels, including pricing, margin, activation costs, sell-through, and profitability.
  • Ability to motivate retailers and distributors by communicating incremental revenue opportunities, attractive margin, and guest experience with low operational lift.
  • Ability to champion premium brands by using compelling storytelling and deep product knowledge to articulate what makes a brand unique.
  • A thorough understanding of distributor dynamics, including communication, motivation, and managing execution through distributor partners.
  • Experience presenting effectively in distributor sales meetings to educate and motivate distributor sales teams.
  • A background in experiential marketing, including consumer education at festivals, large-scale events, or in-store product demonstrations.
Responsibilities
  • Call on chain liquor stores, independent liquor stores, and chain grocery stores in the designated territory.
  • Sell in multiple ZBiotics stock-keeping units and secure multiple high-impact, properly merchandised, correctly priced displays.
  • Manage account inventory levels, ensure adequate inventory, and communicate potential out-of-stock issues to store managers and distributor partners.
  • Secure incremental displays, points of interruption, and shelf placements.
  • Conduct staff education and execute weekly in-store demonstrations.
  • Create and call on targeted on-premise accounts, including high-end hotels, resorts, bars, and restaurants.
  • Secure product distribution, menu placements, and merchandise where possible.
  • Build relationships with waitstaff and create ZBiotics ambassadors through weekly staff education, sampling, and one-to-one interactions.
  • Work with the Retail Marketing Manager to identify brand-awareness campaign opportunities for on-premise accounts.
  • Work regularly with distributor sales managers, supervisors, and account managers across on- and off-premise accounts, focusing on product function and brand education.
  • Collaboratively sell in new distribution, menu placements, and displays while coaching distributor partners on the ZBiotics brand, product quality, and science.
  • Manage distributor product and point-of-sale inventories, support forecasting, maintain days on hand, and support growth across all channels in the state.
  • Partner with the Retail Marketing Manager to deliver consistent retailer onboarding.
  • Provide weekly recaps to distributor sales managers, supervisors, and account managers covering wins, opportunities, follow-up needs, and successes.
  • Lead monthly or bi-monthly training with on- and off-premise distributor teams to build product expertise through presentations and sampling.
  • Conduct merchandising training for distributors in the field or office, focused on optimizing ZBiotics point-of-sale materials and merchandising strategies.
  • Participate in quarterly distributor performance reviews to evaluate strategic progress and alignment and identify new opportunities.
Desired Qualifications
  • Having established professional networks in the Massachusetts and Rhode Island high-end hotel, premium restaurant, and bar sectors is highly preferred.

About the company

ZBiotics creates genetically engineered probiotic supplements designed to break down acetaldehyde, a toxic byproduct of alcohol consumption. The product is taken as a probiotic pill that works in the gut to neutralize acetaldehyde after drinking, helping reduce hangover symptoms. It is sold directly to consumers via its website, with options for one-time purchases or subscriptions. ZBiotics differentiates itself by a clear, people-first approach and ongoing research into other health challenges (dairy intolerance, radiation exposure, lead contamination in water), alongside a commitment to transparency. The company’s goal is to help people manage the after-effects of alcohol while expanding probiotic science and exploring solutions for other health issues.

Company Size

51-200

Company Stage

Series A

Total Funding

$14.4M

Headquarters

San Francisco, California

Founded

2016

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Simplify's Take

What believers are saying

  • ZBiotics sold 15 million-plus Pre-Alcohol shots by July 2026.
  • 2026 hospitality deals added Gurney’s Montauk, Snow Lodge, and seven-city restaurant placements.
  • Management reported 113% CAGR from 2021 through 2025 and profitability.

What critics are saying

  • Both products rely on self-affirmed GRAS, while full FDA submissions remain pending.
  • Alcohol-mitigation claims face regulatory and consumer skepticism if human evidence stays thin.
  • A backlash against engineered microbes would undercut ZBiotics’ entire probiotic platform.

What makes ZBiotics unique

  • ZBiotics pioneered consumer genetically engineered probiotics, launching the first GM probiotic in 2019.
  • Pre-Alcohol and Sugar-to-Fiber target specific problems with proprietary Bacillus subtilis strains.
  • ZBiotics spans DTC and hospitality, including bars, restaurants, resorts, and retail shelves.

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Benefits

Health Insurance

Dental Insurance

401(k) Company Match

Unlimited Paid Time Off

Parental Leave

Home Office Stipend

Commuter Benefits

Hybrid Work Options

Remote Work Options

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

1%

2 year growth

1%
Popin
Jun 14th, 2026
ZBiotics floor display wins Silver OMA.

ZBiotics floor display wins Silver OMA. OMA Silver Award International partnered with ZBiotics to support its transition from a fast-growing direct-to-consumer brand into brick-and-mortar retail with a bold, modern floor display built to stand out in highly competitive store environments. Program Objective After gaining momentum as a direct-to-consumer brand starting in 2019, ZBiotics identified brick-and-mortar expansion as a strategic priority in early 2024. Entering convenience and liquor channels introduced a clear challenge: winning attention in crowded aisles where space is limited and visual competition is high. The objective was straightforward: create a compact, modern floor display that commands attention while preserving valuable floor space. The solution needed to be... Sources include: Great Northern instore

AgFunder
May 14th, 2025
Designer Probiotics Startup Zbiotics Has Sold 8 Million ‘Pre-Alcohol’ Shots, Launched New ‘Sugar To Fiber’ Product

“When I started ZBiotics, I was sure somebody would beat us to the punch,” says Dr. Zack Abbott, the microbiologist behind a genetically engineered probiotic serving as a hangover remedy that many consumers now swear by. “But when we launched three years later, we were the first to market with a genetically engineered probiotic [ZBiotics Pre-alcohol: a shot containing bacteria engineered to expresses an enzyme that breaks down a toxic byproduct of alcohol in the gut]. “Five years later, we launched our second product [ZBiotics Sugar-to-Fiber: which contains containing bacteria engineered to express an enzyme that converts sugars into fibers in the gut] and still nobody else had launched a GM probiotic. I’m not totally sure why, I think maybe there’s a fear that consumers will reject it, but we just haven’t seen that

Beverage Network
Sep 20th, 2024
New Products: Peet's First Concentrated Espresso, Plus Gatorade, Humm, Stash Tea & More

Biotechnology company Zbiotics has announced the launch of Sugar-to-Fiber Probiotic Drink Mix, which it claims to be the first product of its kind to hit the consumer market.

Business Wire
Aug 29th, 2024
ZBiotics, Maker of World’s First Genetically Engineered Probiotics, Raises $12M Series A

ZBiotics, the pioneers carving a new category of genetically engineered probiotics, today announced the close of its $12M Series A funding round, led

FinSMEs
Aug 27th, 2024
ZBiotics Raises $12M in Series A Funding

ZBiotics raises $12M in Series A funding.