Business & Strategy (1)

Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond.It’s an exciting time to be part of Team Olema, withour transformation into a fullyintegrated oncology company well underway, top-line data from our lead program expected later this year,and our first potential commercial launch on the horizon.

Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in the fall which, if successful, could lead to our first potential approval and commercial launch in 2027. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant has the potential to transform the metastatic breast cancer treatment paradigm and access a $15 billion global market opportunity.

Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently reported encouraging Phase 1 monotherapy data from this program across multiple solid tumor types and are advancing patient enrollment in the ongoing combination arms in MBC.

Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and a passionate team dedicated to helping the patients we serve feel better, longer. We possess a deep commitment to our shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day.

If you’re ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what’s beyond.

About the Role >>> Director, Insights and Analytics

Olema Oncology is seeking a Director, Commercial Insights and Analytics to build and lead an integrated insights capability supporting commercial strategy, launch readiness, and lifecycle planning. The role reports to the SVP, Commercial Strategy and Operations.

The Director of Insights and Analytics will serve as a strategic thought partner to Commercial leadership and cross-functional stakeholders, bringing together primary market research, forecasting, and competitive intelligence, to address Olema’s most important business questions.

This individual will develop a deep understanding of customers, patients, and competitors, and translate that understanding into clear implications and recommendations for the business. The role will be responsible for ensuring that Olema has the right insights at the right time to inform decisions ranging from product strategy and launch planning to customer engagement, market development, and investment prioritization.

This is a highly visible, hands-on role for a leader who is comfortable framing ambiguous business questions, designing research and analytical approaches, pressure-testing assumptions, and translating disparate information into executive-ready recommendations.

This role will be based out of either our San Francisco or Boston offices and will require approximately 20%travel.

Your work will primarily encompass:

Integrated Insights & Strategic Decision Support

Serve as the lead insights thought partner to Commercial leadership, identifying the critical questions, risks, and opportunities that should inform strategy and execution.
Lead an integrated insights planning process and synthesize primary research, secondary data, competitive intelligence, epidemiology, and market developments into a cohesive market perspective.
Translate insights into clear implications and recommendations, identifying priority knowledge gaps and the appropriate approach to address them.

Primary Market Research & Customer Insights

Own the primary market research strategy and annual research plan supporting Olema’s portfolio and commercialization priorities.
Design and execute qualitative and quantitative research to generate insights into unmet needs, treatment decisions, product perceptions, adoption barriers, and market opportunities.

Forecasting & Market Assessment

Lead the development, refinement, and governance of patient-based commercial forecasts for Olema’s late-stage portfolio, incorporating epidemiology, patient flow, market research, competitive dynamics, access assumptions, analogs, and clinical and regulatory events.
Develop and communicate scenario-based forecasts to support long-range planning, portfolio prioritization, lifecycle strategy, and business development assessments.

Competitive Intelligence & Market Foresight

Lead commercial competitive intelligence for Olema’s priority disease areas, maintaining an integrated view of competitors, emerging mechanisms, and evolving treatment paradigms.
Lead synthesis around major congresses, data readouts, regulatory events, and other high-impact milestones.

Launch Readiness & Performance Insights

Define the strategic measurement framework for launch, including KPIs and leading indicators spanning patient dynamics, customer engagement, access, adoption, and market evolution.
Partner with analytical colleagues to ensure required data, reporting, and measurement capabilities are in place.
Lead interpretation of launch performance, integrating quantitative signals with primary research, field insights, and competitive context to identify drivers and recommended actions.

Ideal Candidate Profile >>> Commercial Competitive Intelligence Leader

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.

Knowledge:

Bachelor’s degree required; MBA, PhD, or another relevant advanced degree preferred.
Strong understanding of biopharmaceutical commercialization in oncology markets, including patient journeys, customer behavior, treatment dynamics, market access, and launch performance.
Deep expertise in analytical methodologies sufficient to frame business questions, interpret outputs, challenge assumptions, and partner effectively with technical and analytical colleagues.

Experience:

10+ years of progressive responsibility in biopharmaceutical market research, insights, forecasting, competitive intelligence, commercial strategy, management consulting, or related disciplines.
Forward-looking approach to insights generation, including the use of AI-enabled tools, automation, and other modern research methodologies to increase the speed, scale, and quality of market research and strategic insights.
Track record of successfully supporting late-stage assets, launch planning, and in-market brands.
Strong capability in patient-based commercial forecasting, scenario analysis, and market assessment.
Proven ability to integrate primary research, competitive intelligence, secondary analyses, epidemiology, and other evidence into a coherent strategic perspective.
Effective at presenting recommendations and influencing decisions with senior executives and cross-functional leadership teams.
Successful management of agencies, consultants, and other external partners.

Attributes:

Strategic synthesizer: Connects disparate information and identifies the insights that matter most to a business decision.
Structured problem solver: Frames ambiguous questions into clear hypotheses, workstreams, and decision pathways and brings a consulting-style rigor to problem solving.
Collaborative: Works effectively across disciplines and develops strong partnerships across Commercial, Analytics, Data Science, Market Access, Medical Affairs, Clinical Development, Finance, and other functions.
Comfortable with ambiguity: Thrives in a fast-moving environment where information is incomplete and priorities evolve.
High integrity: Brings rigor, objectivity, sound judgment, and appropriate challenge to strategic decision-making.

The base pay range for this position is expected to be $230,000 - $250,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.

#LI-MK1

Important Information >>>

We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated.

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants.

Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you.

Fraud Alert: We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in @olema.com. Our official corporate website is olema.com; our careers page is olema.com/careers; our LinkedIn page is linkedin.com/company/olema-oncology. Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in-person interview.

Director, Commercial Insights and Analytics

Olema Oncology

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