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Revolution Medicines

Clinical-stage oncology company developing RAS inhibitors

Senior Director - Clinical Operations, Global Clinical Vendor Contracts & Budgets

Clinical Research OperationsConfirmed live in the last 24 hours
ContractRedwood City, CA, USA

About the Job

Requirements

  • A Bachelor of Science degree, plus 17 or more years of experience or equivalent, and 10 or more years in a leadership role. An advanced degree is desirable with the following experience alternatives: Master's degree with 15 or more years of experience and 8 or more years of leadership, or Doctoral degree with 13 or more years of experience and 6 or more years of leadership.
  • Expertise in large, multi-site, early- and late-phase, and postmarketing oncology clinical trials.
  • Experience working in growing companies or departments that have created successful processes.
  • A clear understanding of clinical contracting and budget processes.
  • Strong organizational and time-management skills, attention to detail, and the ability to handle multiple tasks efficiently and effectively.
  • Ability to work in a fast-paced company environment and adjust workload based on changing priorities.
  • Experience leading strategic change-management initiatives across clinical operations or an equivalent area.
  • Interpersonal, verbal, and written communication skills, with the ability to interact with colleagues and partners at all experience levels.
  • Understanding of global site budget and contract negotiations to achieve optimal results and develop plans aligned with strategic and operational targets.
  • Ability to produce, interpret, and share complex performance information with a wide variety of audiences.
  • Experience hiring, training, developing, mentoring, and motivating team members to high performance.
  • Ability to plan for the long term and execute stated objectives.
  • Travel may be required, approximately 25%.

Responsibilities

  • Develop and execute the global clinical outsourcing strategy, aligning vendor governance, contracting, and operational frameworks with corporate objectives and clinical development priorities.
  • Provide strategic leadership and oversight for the Global Clinical Vendor Contracts function, driving operational excellence, scalable processes, standardized policies, and continuous improvement across the end-to-end contract lifecycle.
  • Serve as executive sponsor for global clinical vendor relationships, establishing governance models, key performance indicators, preferred provider strategies, and risk-management practices to optimize quality, cost, and delivery.
  • Lead cross-functional partnerships with Clinical Operations, Biometrics, Data Management, Safety, Regulatory, Quality, Finance, Legal, and IT to develop outsourcing strategies, negotiate commercial terms, and ensure seamless execution of clinical programs.
  • Direct strategic sourcing, request for proposal development, vendor evaluation and selection, and contract negotiations, including Master Service Agreements, work orders, change orders, consulting agreements, and clinical budgets.
  • Build and sustain vendor partnerships through performance management, compliance oversight, issue resolution, and executive-level governance, ensuring vendors meet contractual and operational expectations.
  • Anticipate, assess, and resolve complex business, operational, and vendor-relationship challenges, serving as the senior escalation point for critical outsourcing and contract-execution issues.
  • Monitor industry trends and benchmark best practices; implement technologies, contracting models, and process improvements that enhance efficiency, scalability, and business performance.
  • Lead, mentor, and develop the Vendor Contracts organization, fostering collaboration, accountability, strategic thinking, and professional growth while building capabilities for future business needs.
  • Ensure vendor qualification, regulatory compliance, financial stewardship, and contractual risk mitigation through collaboration with Quality Assurance, Legal, Finance, and other stakeholders.
  • Represent Global Clinical Vendor Outsourcing in senior leadership discussions, contributing strategic expertise, data-driven insights, and executive recommendations to support enterprise decisions and delivery of the clinical development portfolio.

Desired Qualifications

  • Familiarity with financial and legal systems or portals.
  • Knowledge or familiarity with clinical trial operations in ex-US regions.
  • Working knowledge of applicable regulations, ICH, and GCP.
  • Experience with global project-level budget builds.
  • Advanced knowledge of Microsoft Word, Excel, PowerPoint, and Smartsheet.
  • A Master's degree with 15 or more years of experience and 8 or more years of leadership, or a Doctoral degree with 13 or more years of experience and 6 or more years of leadership.

About the Company

Revolution Medicines

Clinical-stage oncology company developing RAS inhibitors

Revolution Medicines develops precision oncology drugs focused on cancers driven by RAS mutations. Its RAS(ON) inhibitors are small molecules that bind the active form of RAS to block cancer signaling, with candidates like Daraxonrasib (RMC-6236), Elironrasib (RMC-6291), and Zoldonrasib (RMC-9805) advancing in global Phase 3 trials. The company funds its research through collaborations, royalties, and upfront funding, and has not yet marketed a product. Its goal is to bring effective RAS-targeted therapies to patients and advance multiple candidates through late-stage trials toward approval, supported by strong cash reserves.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Redwood City, CA
Founded
2014

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