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Noetik

AI-native biotechnology company developing precision immunotherapies

Senior Scientist - Spatial Biology

Translational Research & Bench BiologyConfirmed live in the last 24 hours
Full-timeSouth San Francisco, CA, USA

About the Job

Requirements

  • A PhD in molecular biology, genomics, cell biology, biomedical engineering, or a related field.
  • Two to five or more years of industry hands-on experience with spatial transcriptomics platforms such as CosMx, Xenium, or MERFISH.
  • Experience with spatial proteomics platforms and immunofluorescence panel design is highly desirable.
  • Ability to independently troubleshoot wet-lab and imaging-based assay failures and trace issues to their root cause.
  • Knowledge of spatial transcriptomics data quality-control metrics, including transcript count distributions, segmentation quality, dropout and housekeeping-gene diagnostics, batch effects, and spatial artifacts.
  • Ability to enforce standards across a team of junior and senior colleagues.
  • Organizational, oral and written communication, and documentation skills.
  • Computational fluency.

Responsibilities

  • Independently plan, perform, and troubleshoot spatial biology experiments on human tissue samples.
  • Establish and enforce data quality standards across the team's experiments and analysis pipelines.
  • Mentor and train team members on technique, rigor, and quality judgment.
  • Collaborate with Histology and Scientific Operations teams to ensure seamless project execution.
  • Participate in lab team meetings.
  • Lead cross-functional projects with Engineering and Machine Learning team members to design the next generation of data for artificial intelligence model training.

Desired Qualifications

  • Direct CosMx experience.
  • Familiarity with cancer tissue biology and identity marker panels.
  • Proficiency with Python or R for data analysis.
  • Prior experience mentoring or informally leading junior lab staff.

About the Company

Noetik

AI-native biotechnology company developing precision immunotherapies

Noetik is an AI-native biotechnology company that develops precision cancer immunotherapies. It uses advanced machine learning to analyze complex tumor-immune interactions and builds foundational, multimodal models of cells and tissues from large-scale human data. This enables the design of immunotherapies tailored to individual patients. The company partners with pharmaceutical companies and healthcare providers, licensing technologies, conducting research collaborations, and selling proprietary therapeutic solutions. Unlike many firms that apply AI to existing processes, Noetik creates AI-driven models to guide drug discovery and therapy development, aiming to push the capabilities of precision medicine beyond what humans can achieve. The overarching goal is to advance cancer treatment by delivering AI-powered, personalized therapies and enabling clients to develop and commercialize these solutions.

Company size
51-200
Company stage
Series A
Total funding
$54M
Headquarters
South San Francisco, CA
Founded
2022

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