Associate Scientist - Drug Formulation

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition from leading workplace and culture organizations, including Science's Top Employers, Great Place To Work® in the U.S., and Fortune's Best Workplaces in BioPharma.

For patients, for each other, and for the future of science, we’re in. Are you?

About the Role:

We’re looking for an Associate Scientist, Drug Formulation on the Research team to help us expand what’s possible for patients with serious diseases. Reporting to the Senior Scientist, Formulation, you’ll focus on the development, optimization, and characterization of nanoparticle (NP)-based drug delivery systems. You will be part of a multidisciplinary team engaged in non-viral vehicle formulation and characterization, supporting platform build and project-level activities.

What You'll Do:

In this role, you’ll have the opportunity to contribute to the advancement of RNA/gene-based therapeutic programs through hands-on formulation science and rigorous analytical evaluation. You’ll also:

• Work on formulation and characterization of lipid nanoparticles (LNPs) and other nanoparticle-based delivery systems for platform development and project support
• Design and execute formulation studies, including nucleic acid encapsulation into nanoparticle systems, analytical testing, and stability evaluations to finalize formulation compositions for RNA/gene-based therapies
• Perform comprehensive physicochemical characterization of nanoparticle formulations, including size, polydispersity index (PDI), surface charge (zeta potential), encapsulation efficiency, drug loading, and release kinetics
• Apply a broad set of analytical techniques such as DLS, NTA, UV-Vis spectroscopy, SEC, SDS-PAGE, HPLC, and fluorescence-based assays to evaluate nanoparticles and drug products
• Synthesize and develop nanoparticle-based formulations for various therapeutic areas
• Support design, synthesis, and purification of protein bioconjugates, including monoclonal antibody and peptide bioconjugation and dye conjugation, as applicable
• Characterize and evaluate bioconjugates, including physicochemical properties, stability, conjugation efficiency, and binding ability
• Collaborate with team members to troubleshoot formulation challenges and propose data-driven solutions
• Perform data and statistical analyses using Excel and GraphPad Prism
• Maintain accurate, detailed, and timely records in electronic notebooks and generate internal technical reports

Who You Are:

Basic Qualifications

You meet one of the following minimum education and experience requirements:

• Master's degree in Pharmaceutics, Chemistry, Biomedical Engineering, Chemical Engineering, or a related field; OR
• Bachelor's degree and 2 years of experience in Pharmaceutics, Chemistry, Biomedical Engineering, Chemical Engineering, or a related field

You are or you also have:

• Hands-on experience in nanoparticle-based formulation development and analytical characterization

Preferred Qualifications:

• Prior work with nucleic acid delivery systems, especially lipid-based or polymeric nanoparticles
• Experience with nucleic acid encapsulation techniques
• Experience with bioconjugate and targeted delivery
• Proficient in physicochemical and biochemical characterization techniques, including:
  • Dynamic Light Scattering (DLS), Nanoparticle Tracking Analysis (NTA)
  • Size Exclusion Chromatography (SEC)
  • UV-Vis Spectroscopy, HPLC, SDS-PAGE
  • Fluorescence-based assays, protein quantification methods
• Strong data analysis and interpretation skills using GraphPad Prism, Excel, or similar tools
• Familiarity with stability testing, release profiling, and formulation optimization
• Demonstrated ability to independently design, execute, interpret, and present experimental results
• Experience in data processing, analysis, statistics, and data interpretation

Where You’ll Work

This role is based out of our Bridgewater, NJ office and requires full-time, in-person presence to support hands-on collaboration, access specialized equipment, and/or operational needs.

Travel Requirements

Minimal travel expected

#LI-BA

#LI-ONSITE

Pay Range:

$103,000.00-131,000.00 Annual

Life at Insmed
 

At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

Highlights of our U.S. offerings include:

• Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)

• Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration

• 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance

• Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities

• Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Eligibility for specific programs may vary and is subject to the terms and conditions of each plan. 

Current Insmed Employees: Please apply via the Jobs Hub in Workday.

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. For more information, please refer to our Equal Employment Opportunity and Non-Discrimination Statement on our Careers site.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application   or interview process, please contact us by email at [email protected]  and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.

Important Notice for Job Seekers: Insmed will only communicate with candidates from an @insmed.com email address and will never request payment of any kind during the hiring process. If you'd like guidance on recognizing potential recruitment fraud, please reach out to [email protected].