Senior Clinical Operations Manager
SOPHiA GENETICS
Senior Clinical Operations Manager
SOPHiA GENETICS
Cloud-based AI platform for genomic analytics
SOPHiA GENETICS · Rolle, Switzerland (Hybrid) · — · Posted 2026-07-08
Workplace: hybrid
Department: Clinical Operations
Do you bring a strong background in clinical affairs, clinical science, or clinical operations within IVD or molecular diagnostics? Have you designed clinical performance studies and shaped clinical evidence strategy in an IVDR, CE-IVD, or companion diagnostics environment?
If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS team as a Senior Clinical Operations Manager and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.
Enjoy the flexibility of a hybrid work schedule allowing 2 days PW home working, collaborating closely with colleagues in our Rolle, Switzerland corporate office.
We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.
As Clinical Affairs Lead / Senior Clinical Affairs Manager, you will own the clinical performance strategy for validation work, partnering closely with internal stakeholders and external partners to design and deliver clinical performance studies in an IVD and molecular diagnostics context.
This is an individual contributor role with significant seniority and visibility. You will work cross-functionally with Regulatory Affairs, Clinical Operations, CROs, consultants, notified bodies, and biopharma partners, bringing the clinical and scientific expertise needed to shape study design, clinical risk evaluation, and clinical evidence requirements.
We know every background is different, but to be best set for success we see you bringing:
You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth.
Business recognition and accolades include:
Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview:
Our DNA
Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous
Our Virtues
At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn.
At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal
The Process
We use the power of AI to help our partners make decisions. If you’re utilising AI in your search and application process, why not use some of these prompts, or read our AI guide.
‘What impact can I expect to have on the world by working at SOPHiA GENETICS?’
‘I have an interview with SOPHiA GENETICS. What should I know before I meet with them?’
‘I am a *job title* - What can SOPHiA GENETICS offer my career?’
Apply now with your CV and any supporting information.
Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business.
If you need additional support or accommodations for accessibility, please contact our TA team for assistance on [email protected]. SOPHiA GENETICS recruiters only contact candidates from @sophiagenetics.com addresses and never request payment at any stage. Verify any offer before responding.
We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please.
Starting Date: ASAP
Location: Rolle, CH
Contract: Permanent
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Cloud-based AI platform for genomic analytics
Sophia Genetics provides a cloud-based platform called SOPHiA DDM that uses AI and machine learning to analyze digital health data, especially genomic profiles, for healthcare providers, researchers, and pharma companies. It standardizes, computes, and analyzes multimodal data to support diagnosis, therapy selection, analysis, and drug development. Customers own their data and can share insights through the platform, contributing to collective intelligence. The platform is charged on a subscription or access basis, creating a global data-driven medicine ecosystem. The company differentiates itself by enabling data ownership for users, facilitating data sharing among institutions, and handling complex multimodal genomic data to drive better patient outcomes.
Explore more opportunities at SOPHiA GENETICS