C

Commence

Transforms health data into AI-ready insights

Information System Security Officer - Federal Programs

Full-TimePosted on 10/20/2026
$100k - $140k/yr
Senior
Bachelor's
Virginia, USA
RemoteRemote work is limited to candidates in the listed states and DC; estimated travel is 15–25%.
CybersecuritySecurity Governance, Risk & Compliance
No H1B Sponsorship
US Citizenship Required

About the job

Requirements
  • At least 5 years of information assurance or cybersecurity experience, including at least 3 years as an ISSO or A&A lead for federal information systems; a bachelor's degree in a related field or equivalent experience.
  • Personally taken at least one federal system through an initial ATO or reauthorization under NIST SP 800-37/800-53, including SSP authorship and POA&M management in agency-specific GRC platforms.
  • Working knowledge of at least two of CMS ARS/IS2P2, VA 6500, DoD RMF and NIST SP 800-171/CMMC, IRS Publication 1075 & 4812, or DHS 4300A.
  • Ability to read vulnerability and configuration scan output and translate findings into remediation tasks.
  • Familiarity with AWS and Microsoft 365/Azure.
  • CompTIA Security+ or a higher DoD 8140-qualifying certification is required.
  • U.S. citizenship and ability to obtain and maintain federal Public Trust suitability are required.
  • Ability to sit, read, work on a computer, and watch a computer screen for extended periods; occasional standing, walking, hand and finger use, kneeling, or crouching; participation in on-call security incident coverage.
Responsibilities
  • Serve as designated ISSO for assigned federal systems and the primary system-level security liaison to agency ISSOs, Authorizing Officials, assessors, and prime contractor security teams; carry out priorities set by the CIO and ISSM; escalate program-level issues, risk acceptances, and exceptions to the ISSM with a recommended path.
  • Partner with Project Managers to build security and authorization milestones into project plans, assess the security impact of system changes before they ship, and keep federal deliverable dates visible to project and program teams.
  • Run the Security Assessment and Authorization lifecycle under the NIST Risk Management Framework (SP 800-37), from FIPS 199 categorization through authorization, ongoing authorization, and reauthorization.
  • Author and maintain the System Security and Privacy Plan, risk assessment, Privacy Impact Assessment, contingency plan and annual test, incident response plan, configuration management plan, and interconnection agreements for ISSM review.
  • Maintain POA&Ms in agency GRC platforms; review monthly vulnerability and configuration scans against DISA STIGs, CIS benchmarks, and agency baselines; assign and track remediation with Cybersecurity Engineers and IT Operations to agency timelines; prepare ongoing-authorization and continuous-monitoring reports.
  • Lead system-level preparation for CMS Security Controls Assessments and Adaptive Capabilities Testing, VA and DoD assessments, and IRS Safeguards reviews; work with Compliance Analysts on evidence collection and findings response.
  • Maintain compliance with current and future agency requirements, including CMS ARS and IS2P2; VA Handbook 6500 and 6500.6; DFARS 252.204-7012, NIST SP 800-171, and CMMC 2.0 for DoD/DHA; IRS Publication 1075 and 4812; DHS 4300A and Sensitive Security Information handling; and CUI, FISMA, HIPAA, and the Privacy Act.
  • Act as first responder for security and privacy incidents affecting federal data on assigned systems; escalate immediately to the ISSM and CIO; meet agency notification clocks in coordination with the Privacy Officer and prime contractors.
  • Complete system-level contract security deliverables and manage federal personnel security tasks, including Public Trust and e-QIP processing, agency training, rules of behavior, and access attestations.
  • Support the CIO and ISSM with internal audits and control assessments against SOC 2, NIST (CSF, SP 800-53, SP 800-171), HIPAA, HITRUST, and ISO/IEC 27001 frameworks through control testing, evidence preparation, gap analysis, and corrective action tracking.
  • Provide system-specific input to the ISSM and Compliance Analyst, who owns external audits and customer and prime contractor security questionnaires.
Desired Qualifications
  • Experience with FedRAMP and HIPAA is a plus.
  • CISSP, CGRC (formerly CAP), CISA, or CCSP certification is preferred.

About the company

Commence turns unstructured health data from records, claims, and notes into structured, AI-ready data to support decision-making for federal, state, and commercial health programs. Its Amplify platform modularly covers Capture (digitize/standardize), Review (AI classify/summarize), and Clarity (pattern/risk insights), used alone or together with expert oversight from 500+ licensed clinicians. It differentiates itself by combining end-to-end data transformation with clinical review and government-focused workflows, delivering interoperable data-to-decision solutions for program integrity, medical reviews, payments, and quality improvement. Its goal is to improve health outcomes by turning data into actionable insights and efficient operations for public and commercial health partners.

Company Size

51-200

Company Stage

N/A

Total Funding

N/A

Headquarters

Virginia Beach, Virginia

Founded

N/A

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Simplify's Take

What believers are saying

  • September 2026 brought Greg Davis, strengthening federal sales execution and capture.
  • Commence won CMS RMADA 3 placement and new VA, DHA modernization awards.
  • The company serves 60% of Medicare patients across 27 states, creating scale advantages.

What critics are saying

  • Federal budget and policy changes already delayed Commence’s growth plans in 2025.
  • Heavy CMS, VA, and DHA exposure ties revenue to federal procurement cycles.
  • AI health-data rivals like Cotiviti and Optum push deeper into reviews and program integrity.

What makes Commence unique

  • May 2025 merger joined DOMA, Livanta, and Advanta into one federal-health platform.
  • Amplify launched July 2025, unifying Capture, Review, and Clarity for health-data workflows.
  • Over 500 licensed clinicians add human review to AI-driven medical record transformation.

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Benefits

  • Remote Work Options

Company News

Associated Press
Sep 2nd, 2026
Commence appoints Greg Davis as chief growth officer to scale federal health business

Commence, a health services and technology platform backed by Pleasant Land, has appointed Greg Davis as Chief Growth Officer. Davis will oversee expansion of the company's public sector and commercial operations. Davis joins from GDIT, where he served as Vice President of Federal Health, leading a $1.3 billion line of business. Previously at Booz Allen Hamilton, he grew the firm's NIH account from approximately $70 million to $150 million in annual revenue. The appointment follows recent contract wins, including a position on the CMS Research, Measurement, Assessment, Design, and Analysis 3 vehicle, plus new awards supporting modernisation efforts at the Department of Veterans Affairs and Defense Health Agency. Davis replaces Nick Marchand, who is moving to a Chief Strategy Officer role at Pleasant Land.