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Incyte

Biopharmaceutical company pursuing drug discovery.

Manager, Microsoft Cloud Services

System AdministrationUpdated on Nov 10
Full-timeNo salary listedIn-person

About the Job

Requirements

  • Proven technical leadership experience managing cloud, identity, endpoint, infrastructure, or Microsoft platform teams in an enterprise environment.
  • Deep expertise across Microsoft Azure, Microsoft Intune, Microsoft Entra ID, Exchange Online, and Microsoft 365 tenant administration, including architecture, governance, security, integration, and lifecycle management.
  • Strong Azure architecture experience with landing zones, subscriptions, management groups, Azure Policy, role-based access control, networking, private connectivity, shared services, and hybrid integration.
  • Advanced Intune experience with Windows, iOS/iPadOS, Android, Autopilot, mobile device management, mobile application management, compliance, configuration, application deployment, and endpoint security policy architecture.
  • Advanced identity and access management experience with Conditional Access, multifactor authentication, passwordless authentication, Privileged Identity Management, Identity Protection, enterprise applications, access reviews, entitlement management, and hybrid identity.
  • Strong Exchange Online and tenant administration experience including mail flow, domains, connectors, administrative roles, authentication, security dependencies, and licensing.
  • Demonstrated security, compliance, and audit experience with secure baselines, least privilege, risk remediation, control evidence, and work in a regulated or complex enterprise environment.
  • Experience with automation and modern engineering practices, including infrastructure as code, source control, continuous integration and continuous delivery, scripting, application programming interfaces, and configuration management.
  • Strong financial, vendor, and stakeholder management skills with the ability to present technical options, risks, and recommendations to engineering and executive audiences.
  • Bachelor’s degree or equivalent experience in information technology, computer science, engineering, or a related discipline.

Responsibilities

  • Own the Azure strategy and roadmap and translate business, security, compliance, and infrastructure requirements into a prioritized platform plan.
  • Define and govern the Azure enterprise architecture, including management groups, subscriptions, landing zones, resource organization, naming and tagging, Azure Policy, role-based access control, shared services, connectivity, domain name system, private endpoints, logging architecture, and hybrid integration.
  • Serve as the senior technical authority for cloud service selection, architecture patterns, resilience, workload placement, integration, and modernization decisions.
  • Review and approve significant Azure designs and exceptions to ensure alignment with enterprise architecture, cybersecurity, regulatory, supportability, and cost requirements.
  • Establish reusable reference architectures and engineering standards that enable secure, consistent, and efficient cloud adoption.
  • Oversee the Intune platform strategy, architecture, and governance, including conditional access policies.
  • Define standards for securing the Intune platform in collaboration with IT Security and Microsoft, considering the platform roadmap.
  • Provide technical direction to endpoint operations teams and end-user services, excluding routine device support, software fulfillment, and day-to-day endpoint administration.
  • Own the Entra ID architecture and governance model for workforce identities, guest identities, privileged identities, enterprise applications, application registrations, service principals, and managed identities.
  • Define and govern identity security controls, including Conditional Access, multifactor authentication, passwordless authentication, Privileged Identity Management, Identity Protection, access reviews, and entitlement management.
  • Direct identity lifecycle engineering for joiner, mover, and leaver processes, automated provisioning and deprovisioning, role-based access, group governance, and integration with authoritative systems.
  • Establish application authentication and authorization standards for Security Assertion Markup Language, OpenID Connect, OAuth, certificates, secrets, application programming interface permissions, consent, and workload identities.
  • Ensure privileged access is controlled, reviewed, monitored, and auditable using least-privilege and segregation-of-duties principles.
  • Provide platform ownership for Microsoft 365 tenant administration, including tenant configuration, administrative roles, domain management, service-health governance, licensing, and cross-service dependencies within the defined scope.
  • Own the Exchange Online strategy and architecture, including mail flow, accepted domains, connectors, transport controls, authentication, hybrid dependencies, retention alignment, and third-party email security integration.
  • Lead major tenant and messaging initiatives, including migrations, acquisitions, domain changes, service consolidations, security enhancements, and platform lifecycle activities.
  • Monitor Microsoft roadmaps, advisories, and service changes and coordinate impact assessments, testing, communications, and adoption planning for in-scope services.
  • Maintain clear service boundaries with the owners of SharePoint Online, Microsoft Teams, Power Apps, Power Automate, and the Power Platform suite.
  • Maintain the Microsoft cloud security baseline with Cybersecurity through policy, secure configuration standards, identity controls, encryption, key management, centralized logging, and posture assessment.
  • Own remediation plans for platform-level findings from audits, risk assessments, configuration reviews, penetration tests, and internal control evaluations.
  • Define resilience and continuity requirements, including regional strategy, recovery objectives, configuration recovery, dependency mapping, emergency access, and service continuity procedures.
  • Ensure architecture decisions and controls are documented and auditable through current standards, diagrams, decision records, control evidence, exception approvals, and lifecycle documentation.
  • Establish platform guardrails using Azure Policy, role-based access control, privileged workflows, resource locks, tagging, budgets, quotas, approved service catalogs, and automated compliance checks.
  • Drive infrastructure-as-code and policy-as-code adoption using approved tools such as Bicep, Terraform, PowerShell, Microsoft Graph, Azure DevOps, or GitHub-based pipelines.
  • Own cloud financial governance, including cost allocation, forecasting, showback or chargeback support, reservations, savings plans, licensing optimization, consumption analysis, and waste reduction.
  • Maintain a platform lifecycle and technical-debt plan covering unsupported configurations, legacy authentication, expiring credentials, deprecated services, policy exceptions, and modernization priorities.
  • Define performance and health indicators for service quality, identity risk, device compliance, configuration compliance, security posture, cost, capacity, and technical debt without performing daily monitoring activities.
  • Establish the operating model and responsibility assignment matrix across cloud engineering, endpoint operations, infrastructure operations, service desk, Cybersecurity, application teams, and managed service providers.
  • Set technical standards and service expectations for teams performing server provisioning, monitoring, backups, patching, routine incident response, and other day-to-day operational activities.
  • Provide senior escalation and problem-management leadership for complex, recurring, or platform-wide incidents, focusing on root cause, architectural remediation, risk reduction, and prevention of recurrence.
  • Lead governance and service reviews covering roadmap progress, security posture, cost, service performance, risk, lifecycle, vendor delivery, and corrective actions.
  • Lead, coach, and develop a small technical team by setting priorities, assigning accountability, building skills plans, managing performance, and maintaining high engineering standards.
  • Remain technically engaged through architecture reviews, design decisions, escalations, proof-of-concept oversight, and mentoring while delegating execution appropriately.
  • Manage strategic vendors and partners, including statements of work, deliverables, technical quality, service performance, financial commitments, risk, and knowledge transfer.
  • Communicate platform risks, decisions, investments, and tradeoffs to executive and technical audiences and coordinate priorities across business and technology stakeholders.

Desired Qualifications

  • Relevant Microsoft certifications, such as Azure Solutions Architect Expert, Endpoint Administrator Associate, Identity and Access Administrator Associate, Microsoft 365 Administrator Expert, or Cybersecurity Architect Expert.
  • Experience in a pharmaceutical, life sciences, healthcare, or similarly regulated environment with formal change control, data integrity, privacy, and audit-readiness expectations.
  • Experience with Microsoft Defender, Microsoft Sentinel, and Microsoft Purview capabilities as they relate to in-scope cloud, endpoint, identity, messaging, security, and compliance services.
  • Knowledge of recognized governance and security frameworks, such as ITIL, COBIT, NIST, CIS, Zero Trust, Microsoft Cloud Adoption Framework, and Microsoft Well-Architected Framework.

About the Company

Incyte

Biopharmaceutical company pursuing drug discovery.

Incyte develops and sells medicines by discovering and developing new drugs, focusing on diseases in inflammation, autoimmunity, and blood cancers. Its core product, Jakafi (ruxolitinib), is a JAK1/2 inhibitor approved to treat a rare blood cancer and works by blocking JAK enzymes to reduce abnormal blood cell growth. The company also expands its pipeline through research collaborations, partnerships, and acquisitions, such as the 2024 purchase of Escient Pharmaceuticals to strengthen its inflammation and autoimmune portfolio. Unlike some competitors that rely mainly on internal programs, Incyte combines in-house discovery with external collaborations and strategic deals to grow its drug candidates from early research to approved therapies. The goal is to deliver medicines that help patients with serious diseases by building a diverse, clinically validated portfolio of treatments through internal efforts and partnerships.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Wilmington, DE
Founded
1991

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