Senior Director - Clinical Development

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.

For patients, for each other, and for the future of science, we’re in. Are you?

About the Role:

We’re looking for a Senior Director, Clinical Development on the Clinical Development team to help us expand what’s possible for patients with serious diseases. You’ll serve as a clinical leader responsible for supporting two primary activities. First, the role provides clinical evaluation of potential in-licensing or acquisition opportunities coordinated and led by Insmed’s Business Development organization. Second, the role supports cross-functional discussions with Insmed discovery research platforms as molecules advance beyond the Late Lead Optimization milestone that may have potential development in immunological disorders apart from respiratory diseases and as cush there is an expectation that the physician will possess sufficient breadth of experience to contribute meaningfully to initial evaluations across multiple immunological disorders; leveraging external medical experts as needed.

What You'll Do:

In this role, you’ll have the opportunity to provide clinical input into the overall assessment of external molecules as a member of Due Diligence teams. You’ll also:

• Contribute clinical input to cross-functional planning for molecules emerging from Insmed discovery platforms at the Late Lead Optimization stage.

• Serve, as needed, on transition teams for molecules that are in-licensed, acquired, or partnered.

• Maintain awareness of emerging science, competitive landscapes, and evolving global standards of care across relevant disease areas.

• Partner with Global Clinical Development functions to monitor benefit–risk profiles, manage safety signals, and support regulatory communications or meetings for any ongoing studies associated with in-licensed or acquired assets that are in transition to early GPT or GPT formation.

• Collaborate with Global Clinical Development functions to support the design of potential clinical studies and Clinical Development Plans (CDPs) that meet global ICH-GCP, ethical, and regulatory standards.

• Build and maintain strong partnerships with external medical experts supporting development programs for in-licensed or acquired assets that are in transition to earl GPT or GPT formation, as well as emerging programs from Insmed discovery platforms.

Who You Are:

You have an MD, MD/PhD, or equivalent medical training is required, with board certification in an internal medicine specialty that includes immunological disorders such as Rheumatology or Transplantation. Drug development experiences will be considered as relevant, along with at least 7 years of clinical development experience in biotech or pharmaceutical settings, with meaningful drug development experience across modalities, including oral small molecules and biologics; experience with combination drug–device products preferred. Original NDA, MAA, and J-NDA experience is a plus. You are or also have:

• Demonstrated leadership in the design, execution, and interpretation of global Phase 1–2a clinical programs; experience with combination drug–device development and later-stage programs is a plus.

• Strong understanding of global regulatory pathways and expectations, including FDA, EMA, and PMDA.

• Proven ability to lead and influence effectively within cross-functional, matrixed organizations.

• Excellent written and verbal communication skills, with the ability to engage scientific, regulatory, and executive stakeholders.

• Strategic thinking and sound clinical judgment

• High scientific and analytical rigor

• Strong influence and decision-making skills in matrixed environments

• Excellence in communication and external engagement

• Ability to navigate ambiguity and make timely, balanced decisions

• Effective collaboration across global, cross-functional teams

Where You’ll Work

This is a fully remote role. It can be performed effectively from anywhere while staying connected to your Insmed team and community. Occasional travel for team meetings or events will be expected.

Travel Requirements

This role requires occasional domestic/international travel (approximately 10%)

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Pay Range:

$273,000.00-372,000.00 Annual

Life at Insmed
 

At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.

Highlights of our U.S. offerings include:

• Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)

• Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration

• 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance

• Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities

• Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back

Eligibility for specific programs may vary and is subject to the terms and conditions of each plan. 

Current Insmed Employees: Please apply via the Jobs Hub in Workday.

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. For more information, please refer to our Equal Employment Opportunity and Non-Discrimination Statement on our Careers site.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application   or interview process, please contact us by email at [email protected]  and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.