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4D Molecular Therapeutics

Develops gene therapies using AAV vectors

Senior Business Systems Architect

Enterprise ApplicationsConfirmed live in the last 24 hours
Full-timeRemote in USA$167k - $183k

About the Job

Requirements

  • A bachelor's degree in Information Technology, Business Systems, or equivalent is required.
  • Eight to twelve years of hands-on enterprise business systems experience is required.
  • Demonstrated delivery of efficiency gains using AI technologies and tools is required.
  • Strong administration and implementation experience across Procurement/P2P platforms such as Coupa and contract lifecycle management platforms such as Ironclad or equivalent is required.
  • Expert knowledge of procurement, sourcing, supply chain, inventory, supplier onboarding, legal operations, and related controls is required.
  • Experience with SaaS integrations, APIs, middleware, and workflow automation platforms such as Workato is preferred, not required.
  • Experience partnering with and being accountable for outsourced or offshore application support is required.
  • A strong understanding of evidential SOX, ITGC, audit controls, and governance requirements is required.
  • Experience supporting cross-functional business application integrations is required.
  • Strong reporting, analytics, and process design capabilities are required.
  • Familiarity with the Microsoft Azure framework, including Power Platform, is required.
  • Excellent stakeholder management, workload management, and service delivery skills are required.
  • The candidate must be able to work independently with full task ownership and minimal supervision.
  • Strong analytical and problem-solving capabilities are required.
  • Strong execution, follow-through, and prioritization skills across concurrent initiatives are required.
  • High ownership, accountability, attention to detail, and documentation skills are required.
  • Professional certifications in enterprise platforms such as Coupa or Ironclad are preferred, not mandatory.
  • ITIL, TOGAF, or similar technology governance or architecture certification is preferred.
  • Hands-on business systems subject matter expertise with Coupa and contract lifecycle management is required.
  • Proven success delivering AI-enabled process improvements is required.
  • The candidate must be comfortable working directly with auditors, offshore or remote support teams, and business process owners.
  • The candidate must be able to balance strategic projects, day-to-day support, and compliance responsibilities while maintaining hands-on depth and attention to detail.

Responsibilities

  • Serve as the day-to-day IT point of contact and trusted advisor to G&A stakeholders.
  • Translate business requirements into practical, scalable, well-documented solutions.
  • Run hands-on process improvement initiatives and maximize value from existing platforms.
  • Drive user adoption through training, communication, and change management in partnership with the Business Process Owner.
  • Act as the functional and technical owner for applications across the G&A ecosystem, with primary day-to-day responsibility for Procurement, contract lifecycle management, and finance platforms; scope will shift as new G&A applications are implemented.
  • Perform configuration, enhancements, user acceptance testing, security administration, and release and regression testing.
  • Coordinate daily with the outsourced remote managed service provider on ticket triage, backlog prioritization, service-level agreement tracking, and escalation.
  • Support end-to-end business processes from IT, technology, and compliance standpoints, including contract lifecycle management, procurement, supplier data management, spend management, inventory management, and reporting.
  • Partner with stakeholders to evaluate and pilot new business technologies supporting future growth.
  • Identify and build opportunities to leverage AI, Copilot, and workflow automation.
  • Implement automation solutions that measurably improve efficiency and user experience.
  • Evaluate emerging technologies to modernize manual processes in partnership with business users and other IT team members.
  • Collaborate as an application subject matter expert and partner on the design, build, and maintenance of enterprise integrations on modern integration platforms.
  • Execute IT SOX, ITGC, audit, security, and SDLC/change management requirements, including evidence preparation and walkthrough support.
  • Ensure solutions meet compliance, scalability, and operational standards while balancing efficiency.

Desired Qualifications

  • Experience with legal spend or matter management platforms such as Brightflag or equivalent is preferred, not required.
  • Experience with ERP platforms such as NetSuite or comparable systems for financials and inventory is preferred, not required.

About the Company

4D Molecular Therapeutics

Develops gene therapies using AAV vectors

4D Molecular Therapeutics develops gene therapies using its Therapeutic Vector Evolution platform to create adeno-associated virus (AAV) delivery vectors that transport therapeutic genes to patients’ cells. This clinical-stage biotech focuses on genetic diseases such as cystic fibrosis, delivering genetic material through engineered AAV vectors in targeted tissues. Its product approach involves R&D and clinical trials to test safety and efficacy, followed by commercialization through direct sales or partnerships with larger pharmaceutical companies. The company differentiates itself with a proprietary vector evolution technology that enables tailored, precise gene delivery and by pursuing funding and collaborations (e.g., with the Cystic Fibrosis Foundation) to advance therapies like 4D-710. The goal is to bring gene therapies to market to treat serious genetic diseases and improve patient outcomes, funded by equity investments, strategic partnerships, and future product sales.

Company size
201-500
Company stage
IPO
Headquarters
Emeryville, CA
Founded
2013

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