Senior Business Systems Architect
4D Molecular Therapeutics
Senior Business Systems Architect
4D Molecular Therapeutics
Develops gene therapies using AAV vectors
Attention recruitment agencies: All agency inquiries are vetted through 4DMT’s internal Talent Acquisition team. No unsolicited resumes will be accepted. The 4DMT Talent Acquisition team must expressly engage agencies on any requisition. Agencies contacting hiring managers directly will not be tolerated, and doing so may impact your ability to work with 4DMT in the future.
4DMT is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients. The Company’s lead product candidate 4D-150 is designed to be a backbone therapy forming the foundation of treatment of blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF biologics (aflibercept and anti-VEGF-C) with a single intravitreal injection, which substantially reduces the treatment burden associated with current bolus injections. The Company’s lead indication for 4D-150 is wet age-related macular degeneration and the second indication is diabetic macular edema, which are both in Phase 3 development. The Company’s second product candidate is 4D-710, which is the first known genetic medicine to demonstrate successful delivery and expression of the CFTR transgene in the lungs of people with cystic fibrosis after aerosol delivery.
We are taking genetic medicine to new heights and into new disease areas to overcome challenges not addressed by existing medicines. This incredible challenge drives our relentless and talented team. Our people are the essence of our inspiring, innovative and collaborative environment that encourages individual contributions and provides opportunities for career development. We seek the best in the industry who identify with our mission and our bold and innovative results-driven approach. Our Core Values drive the way we work together:
Join us in creating the future of genetic medicine.
GENERAL SUMMARY
4DMT is seeking a Senior Business Systems Architect to serve as a hands-on, business-facing technology leader and trusted IT partner supporting our G&A functions, including Procurement, Legal, Finance & Accounting, Human Resources, and Facilities. This role configures, optimizes, supports, and applies AI and automation to the G&A application portfolio, enabling compliant, scalable business processes that support 4DMT’s commercialization objectives.
A successful candidate will be a hands-on G&A Solutions Architect who personally combines enterprise application and integration build skills, AI innovation, stakeholder engagement, and governance discipline to enable scalable growth and commercial readiness. Open to remote or hybrid candidates that are geographically based on the West Coast.
MAJOR DUTIES & RESPONSIBILITIES:
Business Partnership
Enterprise Applications Support and Solution
AI, Automation & Digital Transformation
Integration, Compliance & Governance
QUALIFICATIONS:
Education:
Experience:
Other Qualifications/Skills:
Physical Requirements and Working Conditions:
Base salary compensation range: $167,000 - $183,000
Develops gene therapies using AAV vectors
4D Molecular Therapeutics develops gene therapies using its Therapeutic Vector Evolution platform to create adeno-associated virus (AAV) delivery vectors that transport therapeutic genes to patients’ cells. This clinical-stage biotech focuses on genetic diseases such as cystic fibrosis, delivering genetic material through engineered AAV vectors in targeted tissues. Its product approach involves R&D and clinical trials to test safety and efficacy, followed by commercialization through direct sales or partnerships with larger pharmaceutical companies. The company differentiates itself with a proprietary vector evolution technology that enables tailored, precise gene delivery and by pursuing funding and collaborations (e.g., with the Cystic Fibrosis Foundation) to advance therapies like 4D-710. The goal is to bring gene therapies to market to treat serious genetic diseases and improve patient outcomes, funded by equity investments, strategic partnerships, and future product sales.
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