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Revolution Medicines

Clinical-stage oncology company developing RAS inhibitors

Executive Director - Clinical Supply Chain

Supply Chain ManagementConfirmed live in the last 24 hours
Full-timeRedwood City, CA, USA

About the Job

Requirements

  • A bachelor's degree in Supply Chain, Business, Engineering, or Life Sciences and 20 or more years of pharmaceutical supply chain experience, or a master's degree (MS or MBA) and at least 18 years of pharmaceutical or biotech supply chain experience.
  • At least 5 years of experience in a leadership or supervisory role.
  • Strong knowledge and experience with cGMP operations for small molecules, end-to-end supply chain, and demand/supply planning.
  • Effective vendor management and oversight skills.
  • CPIM or CSCP certification is a plus.
  • Proven leadership experience hiring, managing, and developing teams.
  • Knowledge and experience with outsourced manufacturing operations (CMOs).
  • Effective, open, and transparent verbal and written communication; strong analytical, communication, and executive-level reporting skills.
  • Ability to work on multiple projects or tasks, meet timelines, and multitask while consistently delivering quality results.
  • Comfort with ambiguity and complexity.

Responsibilities

  • Define and execute the global clinical supply chain strategy aligned with the clinical development pipeline and long-term business goals.
  • Establish strategies and processes to ensure uninterrupted supply for the portfolio across all phases of development.
  • Serve as the subject matter expert for clinical supply chain planning, risk management, and execution.
  • Build scalable processes and infrastructure to support early- through late-phase clinical programs.
  • Plan comparator sourcing management to ensure timely, compliant, and cost-effective product availability.
  • Manage clinical studies executed in conjunction with collaboration partners.
  • Identify and implement clinical supply chain best practices.
  • Oversee end-to-end clinical supply activities, including demand forecasting, protocol reviews, packaging, labeling, distribution, and returns.
  • Ensure uninterrupted supply of investigational medicinal products, including company and comparator products.
  • Champion the monthly Development Operations planning process in collaboration with PDM and Clinical Operations team members.
  • Ensure efficient global clinical supply chain distribution networks are in place.
  • Oversee comparator product demand and supply planning, including comparator drug and co-medication sourcing strategy.
  • Partner with Clinical Operations and Clinical Study Execution Teams in study planning and execution.
  • Collaborate with PDM, Quality, and Regulatory to ensure compliant manufacturing, labeling, and distribution.
  • Work with Finance on budgeting, forecasting, and cost optimization.
  • Work with internal and external partners to develop strategies, identify and mitigate risks, and resolve issues.
  • Ensure clinical supply activities comply with GxP, ICH, FDA, EMA, and global regulatory requirements.
  • Lead inspection-readiness activities as required for global filings and maintain an inspection-ready organization.
  • Build, lead, and mentor a high-performing clinical supply chain organization, driving execution excellence.
  • Establish clear performance metrics, development plans, and succession planning.
  • Foster accountability, continuous improvement, and collaboration.
  • Set clear and actionable team goals.

Desired Qualifications

  • Effective, open, and transparent verbal and written communication skills.
  • Team-oriented, progressive thinker who enjoys participating in an innovative and creative work environment.

About the Company

Revolution Medicines

Clinical-stage oncology company developing RAS inhibitors

Revolution Medicines develops precision oncology drugs focused on cancers driven by RAS mutations. Its RAS(ON) inhibitors are small molecules that bind the active form of RAS to block cancer signaling, with candidates like Daraxonrasib (RMC-6236), Elironrasib (RMC-6291), and Zoldonrasib (RMC-9805) advancing in global Phase 3 trials. The company funds its research through collaborations, royalties, and upfront funding, and has not yet marketed a product. Its goal is to bring effective RAS-targeted therapies to patients and advance multiple candidates through late-stage trials toward approval, supported by strong cash reserves.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Redwood City, CA
Founded
2014

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