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Revolution Medicines

Clinical-stage oncology company developing RAS inhibitors

Associate Director - Biostatistics, Clinical Late Stage

Quantitative Biology & BiostatisticsConfirmed live in the last 24 hours
Full-timeRedwood City, CA, USA

About the Job

Requirements

  • A Ph.D. or M.S. in Statistics or Biostatistics, with at least 5 years of biotech/pharma industry experience as a statistician for Ph.D. holders or 8 years for M.S. holders; level will be determined based on the relevance of experience.
  • Hands-on experience designing and analyzing late-stage oncology trials.
  • Ability to work independently and within a team.
  • Solid knowledge of ICH and other regulatory requirements related to biostatistical activities and clinical trials.
  • Proficiency in SAS and/or R.

Responsibilities

  • Represent biostatistics on study and cross-functional project teams, providing statistical leadership.
  • Lead and manage biostatistical activities to ensure consistency, scientific rigor, and timely deliverables.
  • Provide statistical expertise for the design, analysis, and reporting of clinical studies.
  • Develop statistical analysis plans and analysis specifications, ensuring analyses align with clinical and regulatory objectives.
  • Collaborate with statistical programming to ensure analyses are conducted according to statistical plans and specifications and delivered with high quality.
  • Collaborate with data management and clinical operations to ensure robust CRF and database development and quality data collection.
  • Provide statistical input to global health authority documents, regulatory interactions, and responses to health authority submissions.
  • Influence strategy and inform decision-making through data-driven insights and clear communication of risk and benefit.
  • Collaborate on publications, assist in data interpretation, and ensure consistency and accuracy in data presentation.
  • Contribute to developing functional-level standards, SOPs, and templates.
  • Keep abreast of new developments in statistics, drug development, and regulatory guidance, and share knowledge with functional and cross-functional team members.

Desired Qualifications

  • Hands-on experience designing and analyzing phase 3 oncology trials.

About the Company

Revolution Medicines

Clinical-stage oncology company developing RAS inhibitors

Revolution Medicines develops precision oncology drugs focused on cancers driven by RAS mutations. Its RAS(ON) inhibitors are small molecules that bind the active form of RAS to block cancer signaling, with candidates like Daraxonrasib (RMC-6236), Elironrasib (RMC-6291), and Zoldonrasib (RMC-9805) advancing in global Phase 3 trials. The company funds its research through collaborations, royalties, and upfront funding, and has not yet marketed a product. Its goal is to bring effective RAS-targeted therapies to patients and advance multiple candidates through late-stage trials toward approval, supported by strong cash reserves.

Company size
1,001-5,000
Company stage
IPO
Headquarters
Redwood City, CA
Founded
2014

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