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Senior Clinical Research Jobs

This list tracks 100K+ company job sources and updates hourly with senior clinical research roles spanning trial operations, clinical data, drug safety, regulatory work, and research leadership.

Openings include senior clinical research associate, clinical operations manager, study or trial lead, clinical research coordinator, clinical data leader, drug-safety scientist, clinical affairs specialist, medical director, and research program director. Responsibilities can involve site monitoring, protocol execution, vendor and budget oversight, data review, pharmacovigilance, regulatory submissions, medical interpretation, or leadership of a study portfolio. Pharmaceutical, biotechnology, medical-device, hospital, university, and contract-research settings divide this work differently. A sponsor-side role may oversee vendors and global strategy, a site role may be closer to participants and investigators, and a research organization may emphasize client delivery and travel. Portfolio roles can add prioritization across studies and development milestones. Evaluate seniority through trial phase and complexity, therapeutic expertise, inspection and decision accountability, geographic or portfolio scope, and responsibility for teams, sites, budgets, or external partners.

Decide first whether you want sponsor oversight, site execution, data or safety work, clinical affairs, or scientific leadership. Within that function, compare therapeutic area, trial phase, study count, geographic scope, and responsibility for vendors, sites, budgets, or people. Establish which decisions require medical, scientific, operational, or regulatory authority and where the role escalates issues. The employer posting should confirm GCP and other quality expectations, required clinical license or degree, regulatory experience, travel, and onsite or remote terms. Use any stated interview format to prepare examples of protocol judgment, escalation, inspection readiness, stakeholder communication, and protection of data quality and participant safety. Employer, location, compensation, and sponsorship filters assist with practical constraints, while licensure, authorization, and eligibility requirements must be confirmed at the source.

Browse and filter the list for free. An optional free account can save clinical-research roles, record application steps, and provide Copilot. Keep trial phase, travel, and credential details with the correct role.

2,694
roles in this list
1,538
added this week
Featuring roles at
Canva
Netflix
Notion
Visa
Capital One
& 100K+ more
Got questions?

Explore our FAQ section to learn more.

This list covers senior full-time roles in clinical research, clinical research operations, clinical development, medical research, clinical data science, and biostatistics. Titles can include senior CRA, clinical trial manager, clinical operations lead, study director, and clinical development director.

Clinical research operations usually focuses on running studies, sites, vendors, timelines, documentation, and trial execution. Clinical development is often closer to study strategy, medical evidence, protocol design, endpoints, and development decisions.

Highlight trial phases, therapeutic areas, site management, protocol execution, vendor oversight, data quality, regulatory documentation, monitoring, timelines, patient recruitment, inspection readiness, and measurable improvements to study execution.

Some clinical development or medical roles require advanced clinical credentials, but many clinical operations, CRA, trial management, data, and biostatistics roles value direct trial experience, regulatory knowledge, and operational judgment.

Expect questions about protocol deviations, site issues, timelines, monitoring, vendor management, patient recruitment, data quality, risk management, GCP, inspection readiness, and how you communicate across clinical, medical, regulatory, and data teams.

Compare therapeutic area, trial phase, sponsor or CRO model, travel, workload, manager support, vendor complexity, compensation, career path, and whether the role builds expertise in operations, science, data, or leadership.

Medical science liaison and medical affairs roles can appear near clinical research but are usually field medical or stakeholder-facing roles rather than trial operations or clinical research execution.